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Time	Room	Session
08:00 08:15	08:00-08:15	Riverfront	Welcome and Introductory Comments Full Details
08:15 09:30	08:15-09:30	Riverfront	Insights from Islet Biology for Making Stem Cell-Derived Islets Full Details Julie B Sneddon, United States Interrogating human pancreas development for improved generation of stem cell-derived islets Julie B Sneddon, United States Interrogating human pancreas development for improved generation of stem cell-derived islets Raphael Scharfmann, France Insights from islet biology for making stem cell-derived islets Raphael Scharfmann, France Insights from islet biology for making stem cell-derived islets Efsun Arda, United States Single-cell analysis of pancreatic endocrine progenitors Efsun Arda, United States Single-cell analysis of pancreatic endocrine progenitors Juan Dominguez-Bendala, United States Making a pancreas, taming a pancreas: to islet replacement and beyond Juan Dominguez-Bendala, United States Making a pancreas, taming a pancreas: to islet replacement and beyond Doug Melton, United States Panel Discussion and Q&A Doug Melton, United States Panel Discussion and Q&A
09:30 - 10:00 \| Networking Coffee Break Parkview & Somerset Sponsored by:
10:00 11:15	10:00-11:15	Riverfront	Optimizing Differentiation to Stem Cell Beta Cells Full Details Shuibing Chen, United States Human pluripotent stem cell-derived pancreatic beta cells for disease modeling Shuibing Chen, United States Human pluripotent stem cell-derived pancreatic beta cells for disease modeling Jeffrey Millman, United States Stem cell-derived islets: A promising solution for diabetes treatment Jeffrey Millman, United States Stem cell-derived islets: A promising solution for diabetes treatment Timo Otonkoski, Finland Mechanisms of SC-beta cell functional maturation Timo Otonkoski, Finland Mechanisms of SC-beta cell functional maturation Quinn Peterson, United States Building a better islet: Control of endocrine cell fate decisions in culture Quinn Peterson, United States Building a better islet: Control of endocrine cell fate decisions in culture Cristina Nostro, Canada Panel Discussion and Q&A Cristina Nostro, Canada Panel Discussion and Q&A
11:15 11:45	11:15-11:45	Riverfront	Keynote Address: Vertex Trial Results Update Full Details James Markmann, United States Vertex Trial Results Update James Markmann, United States Vertex Trial Results Update
11:45 - 12:45 \| Lunch Break Parkview
12:45 13:00	12:45-13:00		Group Photo Full Details
13:00 14:15	13:00-14:15	Riverfront	Other Cells of the Islet Product: Should We Pay More Attention to the Deep Space Between the Stars? Full Details Mark Huising, United States The physiological impact of other islet endocrine cells on beta cell function Mark Huising, United States The physiological impact of other islet endocrine cells on beta cell function Maike Sander, Germany Vascularized SC-islet organoids Maike Sander, Germany Vascularized SC-islet organoids Ryo Ito, Japan Strategies for reducing non-endocrine cells in stem cell-derived islets Ryo Ito, Japan Strategies for reducing non-endocrine cells in stem cell-derived islets Leendert Looijenga, Netherlands Monitoring and controlling tumorigenicity of stem cell products Leendert Looijenga, Netherlands Monitoring and controlling tumorigenicity of stem cell products Esther Latres, United States Panel Discussion and Q&A Esther Latres, United States Panel Discussion and Q&A
14:15 - 14:45 \| Networking Coffee Break Parkview & Somerset
14:45 16:25	14:45-16:25	Riverfront	Best Abstracts Session Full Details Xiaofeng Huang, United States Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids Xiaofeng Huang, United States Restoring glucose homeostasis with stomach-derived human insulin-secreting organoids Valeria Sordi, Italy Identification of beta cell differentiation-prone iPSC clones Valeria Sordi, Italy Identification of beta cell differentiation-prone iPSC clones Nerea Cuesta Gomez, Canada AKT inhibitor AT7867 potentiates pancreatic progenitor differentiation of human pluripotent stem cells Nerea Cuesta Gomez, Canada AKT inhibitor AT7867 potentiates pancreatic progenitor differentiation of human pluripotent stem cells Chencheng Wang, Norway Nutrient control of insulin secretion in stem cell-derived islets Chencheng Wang, Norway Nutrient control of insulin secretion in stem cell-derived islets Andres J Garcia, United States Synthetic hydrogels for islet/SC vascularization, engraftment, and immune acceptance Andres J Garcia, United States Synthetic hydrogels for islet/SC vascularization, engraftment, and immune acceptance Ji Lei, United States Allogeneic pancreatic islets transplanted to a bioengineered omentum achieves euglycemic control in a diabetic NHP model Ji Lei, United States Allogeneic pancreatic islets transplanted to a bioengineered omentum achieves euglycemic control in a diabetic NHP model Nidheesh Dadheech, Canada Complete suspension culture biomanufacturing of human pluripotent stem cell-derived islets for diabetes cell therapy Nidheesh Dadheech, Canada Complete suspension culture biomanufacturing of human pluripotent stem cell-derived islets for diabetes cell therapy Jolien R Nijns, Belgium Vascularization of beta cell mass in device-encapsulated hPSC-derived pancreatic endoderm implants in subcutis of nude rats Jolien R Nijns, Belgium Vascularization of beta cell mass in device-encapsulated hPSC-derived pancreatic endoderm implants in subcutis of nude rats Harald Stover, Canada Immuno-privileged hydrogels protect functionality of islets transplanted into immunocompetent diabetic animals without immunosuppression Harald Stover, Canada Immuno-privileged hydrogels protect functionality of islets transplanted into immunocompetent diabetic animals without immunosuppression Praveen Kumar Raju Pedabaliyarasimhuni, Canada Pre-vascularized bioartificial pancreas device development using 3D printing Praveen Kumar Raju Pedabaliyarasimhuni, Canada Pre-vascularized bioartificial pancreas device development using 3D printing Julia Thorngren, Sweden Transplanted pluripotent stem cell-derived islets engraft superior to human islets Julia Thorngren, Sweden Transplanted pluripotent stem cell-derived islets engraft superior to human islets Adriana Migliorini, Canada Deciphering the hematopoietic pancreatic niche during human fetal development Adriana Migliorini, Canada Deciphering the hematopoietic pancreatic niche during human fetal development Matthias Austen, Germany Manufacturing of optimized human islet-like clusters (ILCs) from iPSCs and functional testing of an ILC + Cell PouchTM combination in vivo Matthias Austen, Germany Manufacturing of optimized human islet-like clusters (ILCs) from iPSCs and functional testing of an ILC + Cell PouchTM combination in vivo
16:25 - 16:35 \| Stretch Break
16:35 17:40	16:35-17:40	Riverfront	Transdifferentiation, Proliferation and Stem Cell Gene Editing Full Details Domenico Accili, United States Treating diabetes by converting gut cells to beta cells Domenico Accili, United States Treating diabetes by converting gut cells to beta cells Andrew Stewart, United States Human beta cell regenerative drug therapy for diabetes: a journey from impossible to possible Andrew Stewart, United States Human beta cell regenerative drug therapy for diabetes: a journey from impossible to possible Valentin Sluch, United States CRISPR modified stem cells as a therapy for type 1 diabetes Valentin Sluch, United States CRISPR modified stem cells as a therapy for type 1 diabetes James Shapiro, Canada Panel Discussion and Q&A James Shapiro, Canada Panel Discussion and Q&A
17:45 19:00	17:45-19:00	Parkview	Networking Reception Sponsored by: Full Details

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